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Photopheresis Work

How can THERAKOS™ Photopheresis help?


Cutaneous T-cell lymphoma (CTCL), graft-versus-host disease (GVHD) and solid organ transplant (SOT) rejection are all diseases that involve an imbalance in your immune system. THERAKOS™ Photopheresis therapy is thought to help restore your body's natural ability to maintain a balanced immune system.11

When your white blood cells are treated and then returned to your body, they may help your immune system to restore balance.

Regulating cells versus damaging cells

Here’s how it works. There are several types of T-cells in the body. Think of these T-cells as “regulating” cells and “damaging” cells.

In a healthy immune system, the regulating cells prevent the damaging cells from creating an imbalance in the body. But in someone with CTCL, GVHD or SOT rejection there may be fewer regulating cells present to maintain this balance, so too many damaging cells will be produced by the immune system.

THERAKOS™ Photopheresis targets the regulating cells, resulting in a restoration of balance in the immune system – also called immunomodulation.

Photopheresis:A balanced immune system Image

Although it is not yet completely understood how THERAKOS™ Photopheresis works, it appears that when treated cells are put back into your body, the regulating cells regain control over the damaging cells and help restore balance in your body.


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